MCHR1: Small Molecules and Peptides
MCHR1 is the receptor for melanin-concentrating hormone MCH. It is coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis. The hypothalamic neuropeptide MCH, and its only receptor MCHR1, play important roles in energy homeostasis, anxiety, and sleep regulation. MCHR1 is also important in regulating metabolic responses upon various environmental stimuli such as high-fat diet.
3 results for "MCHR1 Small Molecules and Peptides" in Products
3 results for "MCHR1 Small Molecules and Peptides" in Products
MCHR1: Small Molecules and Peptides
MCHR1 is the receptor for melanin-concentrating hormone MCH. It is coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis. The hypothalamic neuropeptide MCH, and its only receptor MCHR1, play important roles in energy homeostasis, anxiety, and sleep regulation. MCHR1 is also important in regulating metabolic responses upon various environmental stimuli such as high-fat diet.
MCH1 antagonist
| Chemical Name: | 6-(4-Chlorophenyl)-3-[3-methoxy-4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-thieno[3,2-d]pyrimidin-4(3H)-one |
| Purity: | ≥95% (HPLC) |
Potent and selective MCH1 antagonist
| Chemical Name: | N-[3-[1-[[4-(3,4-Difluorophenoxy)phenyl]methyl]-4-piperidinyl]-4-methylphenyl]-2-methylpropanamide hydrochloride |
| Purity: | ≥98% (HPLC) |
Selective melanin-concentrating hormone receptor 1 (MCH1R) antagonist
| Chemical Name: | 4-[(4-Fluorophenyl)methoxy]-1-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2(1H)-pyridinone |
| Purity: | ≥97% (HPLC) |
