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1 result for "MAP3K8/Tpl2/COT" in Products
MAP3K8/Tpl2/COT Products
MAP3K8, also called Tpl2 (tumor progression locus 2) or COT (Cancer Osaka Thyroid oncogene), is a cytosolic Ser/Thr kinase. MAP3K8 is one of the MAP kinase kinase (MAPKK) kinases that regulates the ERK1/ERK2 pathway in response to IL-1, facilitating IL-8 and MIP-1 beta production. MAP3K8 activates I kappa B kinases and induces the nuclear production of NF-kappa B.
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #634130
Applications:
WB