MAGEA2 Products

MAGEA2, also known as Melanoma-associated antigen 2, is a 314 amino acid protein that is 35 kDa, Reduces p53/TP53 transactivation function through recruitment of HDAC3 to p53/TP53 transcription sites, represses p73/TP73 activity, proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination by TRIM28 potentially in presence of Ubl-conjugating enzyme ...