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84 results for "Lyp" in Products

Lyp Products

Lyp, also called LyPTP, protein tyrosine phosphatase, nonreceptor-type 22, and PEST-domain phosphatase, dephosphorylates tyrosine residues in proteins. Found primarily in bone marrow and lymphoid cell lines, an R620W gain-of-function mutation in Lyp has been associated with susceptibility to autoimmune diseases such as type I diabetes, rheumatoid arthritis, and lupus erythematosus. Mature PEP knockout mice have an excess of CD8 positive T cells and an exaggerated antigen-induced proliferative response.

Reactivity: Human
Details: Goat IgG Polyclonal
Applications: IHC, WB, ELISA, ICC/IF, Flow
Immunocytochemistry/ Immunofluorescence: Lyp/PTPN22 Antibody [NBP2-69989]
(5)
Reactivity: Human, Mouse, Porcine
Details: Mouse IgG2a Kappa Monoclonal Clone #4F6
Applications: WB, ELISA, Mycoplasma
Western Blot: Lyp/PTPN22 Antibody (4F6) [H00026191-M01]
(3)
Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: IHC
Lyp/PTPN22 Antibody - BSA Free Immunohistochemistry-Paraffin: Lyp/PTPN22 Antibody [NBP1-81277]
(4)
Reactivity: Human
Details: Goat IgG Polyclonal
Reactivity: Human
Details: Goat IgG Polyclonal
Reactivity: Human
Details: Mouse IgG2b Monoclonal Clone #340113
Reactivity: Human
Details: Mouse IgG2b Monoclonal Clone #340113
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