9 results for "Jak2 Small Molecules and Peptides" in Products
Jak2 Small Molecules and Peptides
Jak1, Jak 2, and Jak3 belong to the Janus Kinases family of protein tyrosine kinases that couple to cytokine receptors once activated by their corresponding ligands. Activation of Jak family members occurs via phosphorylation at two adjacent tyrosine residues as well as potentially one or more serine residues. Jaks activate members of the STAT family of transcription factors by phosphorylating critical tyrosine regulatory sites.
Jak1 is required for the activation of STAT1 and STAT2 in ...
Potent, selective inhibitor of MEK1 and 2
Potent JAK inhibitor
JAK2/STAT3 signaling pathway inhibitor
EGFR-kinase inhibitor. Also JAK2, JAK3 inhibitor
JAK2, FLT3 and TrkA inhibitor; also inhibits AurA and AurB
Potent and selective JAK1/JAK2 inhibitor; orally bioavailable
Highly potent JAK1 and JAK2 inhibitor; also inhibits JAK3 and Tyk2
Potent pan-JAK inhibitor; induces intermediate mesoderm; cell-permeable
Phosphate salt of Ruxolitinib (Cat. No. 7064); potent and selective JAK1/JAK2 inhibitor
