IL-12 R beta 2 Products
The biological activities of IL-12 are mediated through a receptor complex composed of two class I cytokine receptor subunits designated IL-12 R beta 1 and IL-12 R beta 2. Both subunits are required for high-affinity binding and activity of IL-12. IL-12 R beta 1 binds specifically to IL-12 p40, a subunit of the heterodimeric IL-12, and is also a subunit of the IL-23 receptor complex, while IL-12 R beta 2 binds IL-12 p35. IL-12 Rs are predominantly expressed on NK cells and activated T (Th1) cells with some expression also on dendritic cells. Both IL-12 R subunit extracellular domains are composed of three fibronectin-like domains and two cytokine receptor homology domains. IL-12R beta 2 also has an extracellular Ig-like domain.
169 results for "IL-12 R beta 2" in Products
169 results for "IL-12 R beta 2" in Products
IL-12 R beta 2 Products
The biological activities of IL-12 are mediated through a receptor complex composed of two class I cytokine receptor subunits designated IL-12 R beta 1 and IL-12 R beta 2. Both subunits are required for high-affinity binding and activity of IL-12. IL-12 R beta 1 binds specifically to IL-12 p40, a subunit of the heterodimeric IL-12, and is also a subunit of the IL-23 receptor complex, while IL-12 R beta 2 binds IL-12 p35. IL-12 Rs are predominantly expressed on NK cells and activated T (Th1) cells with some expression also on dendritic cells. Both IL-12 R subunit extracellular domains are composed of three fibronectin-like domains and two cytokine receptor homology domains. IL-12R beta 2 also has an extracellular Ig-like domain.
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #918102 |
| Applications: | Block |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #305719 |
| Applications: | Flow |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #305719 |
| Applications: | Flow |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #305719 |
| Applications: | Flow |
| Source: | NS0 |
| Accession #: | Q99665-1 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #622509 |
| Applications: | WB |
| Source: | CHO |
| Accession #: | Q99665.1 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | P97378 |
| Applications: | BA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #305719 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Block |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Block |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #622509 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Block |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Block |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #622509 |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #305719 |
| Applications: | DirELISA |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #918102 |
| Applications: | Block |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #622509 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Block |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Block |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #622509 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Block |