IL-10: Proteins and Enzymes
IL-10 (Interleukin-10) functions as an anti-inflammatory cytokine by inhibiting the expansion and activation of Th1 cells and Th17 cells and by promoting the development of M2 macrophages and regulatory T cells (Treg). Within a tumor microrenvironment, however, IL-10 can inhibit the expansion of both Treg and myeloid-derived suppressor cells (MDSC). IL-10 exerts protective effects including limiting tissue damage in arthritic inflammation and promoting muscle regeneration after injury, but it also contributes to the persistence of viral infections. IL-10 signals through a receptor complex composed of IL-10 R alpha and IL-10 R beta. IL-10 R beta additionally associates with IL-20 R alpha, IL-22 R alpha 1, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29.
24 results for "IL-10 Proteins and Enzymes" in Products
24 results for "IL-10 Proteins and Enzymes" in Products
IL-10: Proteins and Enzymes
IL-10 (Interleukin-10) functions as an anti-inflammatory cytokine by inhibiting the expansion and activation of Th1 cells and Th17 cells and by promoting the development of M2 macrophages and regulatory T cells (Treg). Within a tumor microrenvironment, however, IL-10 can inhibit the expansion of both Treg and myeloid-derived suppressor cells (MDSC). IL-10 exerts protective effects including limiting tissue damage in arthritic inflammation and promoting muscle regeneration after injury, but it also contributes to the persistence of viral infections. IL-10 signals through a receptor complex composed of IL-10 R alpha and IL-10 R beta. IL-10 R beta additionally associates with IL-20 R alpha, IL-22 R alpha 1, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29.
| Source: | E. coli |
| Accession #: | P22301.1 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | P22301.1 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | NP_034678 |
| Applications: | BA |
| Source: | Sf 21 (baculovirus) |
| Accession #: | P22301 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | P29456.1 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | AAF63437 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | Q29055 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | XP_855560 |
| Applications: | BA |
| Source: | HEK293 |
| Accession #: | P22301.1 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | P03180 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | P29456 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | P22301.1 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | Q28374 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | AAK94013 |
| Applications: | BA |
| Source: | HEK293 |
| Accession #: | P18893.2 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | NP_034678 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | P55029.2 |
| Applications: | BA |
| Source: | Sf 21 (stably transfected) |
| Accession #: | P22301 |
| Applications: | BA |
| Applications: | PAGE, Bioactivity |
![SDS-PAGE: Recombinant Human IL-10 Protein [NBP2-35015]](https://resources.bio-techne.com/images/products/Human-IL-10-Protein-SDS-Page-NBP2-35015-img0001.jpg "SDS-PAGE: Recombinant Human IL-10 Protein [NBP2-35015]")
| Applications: | PAGE, Bioactivity |
![SDS-PAGE: Recombinant Mouse IL-10 Protein [NBP2-35101]](https://resources.bio-techne.com/images/products/Mouse-IL-10-Protein-SDS-Page-NBP2-35101-img0001.jpg "SDS-PAGE: Recombinant Mouse IL-10 Protein [NBP2-35101]")
![SDS-PAGE: Recombinant Rat IL-10 Protein [NBP2-61341]](https://resources.bio-techne.com/images/products/Recombinant-Rat-IL-10-Protein-SDS-Page-NBP2-61341-img0002.jpg "SDS-PAGE: Recombinant Rat IL-10 Protein [NBP2-61341]")