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3 results for "HNF-4 alpha/NR2A1" in Products
HNF-4 alpha/NR2A1 Products
Hepatocyte Nuclear Factor 4 alpha (HNF4 alpha; NR2A1) is a member of the orphan nuclear receptor family. HNF4 alpha is expressed in the liver, kidney, intestine and pancreas. Mutation of HNF4 alpha in humans has been associated with maturity-onset diabetes of the young type 1 (MODY1). HNF4 binds to DNA as an exclusive homodimer. The HNF4 alpha gene is alternatively spliced and may generate up to nine different isoforms, HNF4 alpha 1 through HNF4 alpha 9. The expression of HNF-4 gamma (NR2A2) is observed in the pancreas, kidney, small intestine, and testes with no expression detected in the liver. The level of HNF-4 gamma is less 10% than that of HNF-4 alpha.
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #843716
Applications:
WB, Flow, ICC/IF
Reactivity:
Human, Mouse, Rat
Details:
Mouse IgG1 Monoclonal Clone #OTI2H2
Applications:
IHC, WB
