7 results for "HGFR/c-MET Small Molecules and Peptides" in Products
HGFR/c-MET Small Molecules and Peptides
HGFR (Hepatocyte Growth Factor Receptor), also known as Met, is a receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. In the absence of ligand, HGFR forms noncovalent complexes with a variety of membrane proteins including CD44v6, CD151, EGFR, Fas, Integrin alpha 6 beta 4, Plexins B1, 2, 3, and MSPR/Ron. Ligation of one complex component triggers activation of the other, followed by cooperative signaling effects. Formation of some of these ...
Highly selective MET inhibitor
VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
Potent and selective MET inhibitor
Potent c-MET/ALK inhibitor
Potent VEGFR, PDGFRβ and KIT inhibitor
Selective and potent c-MET kinase inhibitor
Selective and potent c-MET kinase inhibitor