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5 results for "HDAC10 Small Molecules and Peptides" in Products
HDAC10 Small Molecules and Peptides
In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by ...
Histone deacetylase inhibitor
Alternate Names:
VPA,Sodium Valproate
Chemical Name:
Sodium 2-propylpentanoate
Potent histone deacetylase inhibitor
Chemical Name:
(2E,4E,6R)-7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
Purity:
≥95%
Class I and II HDAC inhibitor
Alternate Names:
Vorinostat
Chemical Name:
N-Hydroxy-N'-phenyloctanediamide
Purity:
≥98%
Histone deacetylase inhibitor
Alternate Names:
4-PB,Sodium phenylbutyrate
Chemical Name:
4-Phenylbutyric acid, sodium salt
Purity:
≥98%
Potent class I and IIb HDAC inhibitor
Chemical Name:
5-[(4-[1,1'-Biphenyl]-4-yl-1,6-dihydro-6-oxo-2-pyrimidinyl)thio]-N-hydroxypentanamide
Purity:
≥98%