GLI-1 Products
GLI family proteins are zinc finger transcription factors best known for regulating the expression of gene targets of Hedgehog (Hh) signaling. They share homology with the Drosophila Ci protein, which serves as a mediator of Hh responses in the fly. GLI-1 is a member of the Krupple family of zinc finger proteins. GLI-1 is activated by the sonic hedgehog pathway and influences transcription of a variety of target genes by binding to the consensus site 5CGGGTGGTC3. GLI- activation leads to cellular proliferation and anti-apoptotic activities based on target genes activated.
243 results for "GLI-1" in Products
243 results for "GLI-1" in Products
GLI-1 Products
GLI family proteins are zinc finger transcription factors best known for regulating the expression of gene targets of Hedgehog (Hh) signaling. They share homology with the Drosophila Ci protein, which serves as a mediator of Hh responses in the fly. GLI-1 is a member of the Krupple family of zinc finger proteins. GLI-1 is activated by the sonic hedgehog pathway and influences transcription of a variety of target genes by binding to the consensus site 5CGGGTGGTC3. GLI- activation leads to cellular proliferation and anti-apoptotic activities based on target genes activated.
| Reactivity: | Human, Mouse, Canine, Porcine |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +2 More |
![Knockdown Validated: GLI-1 Antibody - BSA Free [NB600-600]](https://resources.bio-techne.com/images/products/GLI-1-Antibody-Immunohistochemistry-Paraffin-NB600-600-img0005.jpg "Immunohistochemistry: GLI-1 Antibody - BSA Free [NB600-600]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Func, MA |
![Immunohistochemistry: GLI-1 Antibody - BSA Free [NBP1-78259]](https://resources.bio-techne.com/images/products/GLI-1-Antibody-Immunohistochemistry-NBP1-78259-img0009.jpg "Immunohistochemistry: GLI-1 Antibody - BSA Free [NBP1-78259]")
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ChIP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4E2 |
| Applications: | IHC, WB, ICC/IF, KD |
![Western Blot: GLI-1 Antibody (OTI4E2) [NBP2-45872]](https://resources.bio-techne.com/images/products/GLI-1-Antibody-4E2-Western-Blot-NBP2-45872-img0011.jpg "Western Blot: GLI-1 Antibody (OTI4E2) [NBP2-45872]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: GLI-1 Antibody [NBP2-24662]](https://resources.bio-techne.com/images/products/GLI-1-Antibody-Western-Blot-NBP2-24662-img0006.jpg "Western Blot: GLI-1 Antibody [NBP2-24662]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1B9F8 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +1 More |
![Western Blot: GLI-1 Antibody (1B9F8)BSA Free [NBP2-52475]](https://resources.bio-techne.com/images/products/GLI-1-Antibody-1B9F8-Western-Blot-NBP2-52475-img0005.jpg "Western Blot: GLI-1 Antibody (1B9F8)BSA Free [NBP2-52475]")
GLI antagonist; inhibits Hedgehog (Hh) signaling
| Chemical Name: | 2,2'-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethylbenzenamine |
| Purity: | ≥98% (HPLC) |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #JF09-08 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: GLI-1 Antibody (JF09-08) [NBP2-66867]](https://resources.bio-techne.com/images/products/GLI-1-Antibody-JF09-08-Western-Blot-NBP2-66867-img0007.jpg "Western Blot: GLI-1 Antibody (JF09-08) [NBP2-66867]")
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2B Monoclonal Clone #CL12193 |
| Applications: | IHC, ICC/IF |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #HL247 |
| Applications: | IHC, WB |
![Western Blot: GLI-1 Antibody (HL247) [NBP3-13667]](https://resources.bio-techne.com/images/products/GLI-1-Antibody-HL247-Western-Blot-NBP3-13667-img0004.jpg "Western Blot: GLI-1 Antibody (HL247) [NBP3-13667]")
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #CL12192 |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: GLI-1 Antibody [NBP3-21211] -](https://resources.bio-techne.com/images/products/nbp3-21211_mouse-gli-1-mab-cl12192-45202315534353.jpg "Immunohistochemistry-Paraffin: GLI-1 Antibody [NBP3-21211] -")
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2A Monoclonal Clone #GT249 |
| Applications: | IHC, WB |
![Western Blot: GLI-1 Antibody (GT249) [NBP3-13674]](https://resources.bio-techne.com/images/products/GLI-1-Antibody-GT249-Western-Blot-NBP3-13674-img0001.jpg "Western Blot: GLI-1 Antibody (GT249) [NBP3-13674]")
| Applications: | AC |
| Applications: | AC |
| Applications: | WB, ELISA, MA, AP |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL12191 |
| Applications: | WB, ICC/IF |
![Immunocytochemistry/Immunofluorescence: GLI-1 Antibody [NBP3-21210] -](https://resources.bio-techne.com/images/products/nbp3-21210_mouse-gli-1-mab-cl12191-45202315531347.jpg "Immunocytochemistry/Immunofluorescence: GLI-1 Antibody [NBP3-21210] -")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: GLI-1 Antibody [NBP2-68877]](https://resources.bio-techne.com/images/products/GLI-1-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-68877-img0001.jpg "Immunocytochemistry/ Immunofluorescence: GLI-1 Antibody [NBP2-68877]")
| Applications: | ELISA |
| Applications: | ELISA |
| Applications: | AC |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: GLI-1 Antibody [NBP2-56230]](https://resources.bio-techne.com/images/products/GLI-1-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-56230-img0001.jpg "Immunocytochemistry/ Immunofluorescence: GLI-1 Antibody [NBP2-56230]")
| Applications: | WB |
![Western Blot: GLI-1 Overexpression Lysate [NBL1-11109]](https://resources.bio-techne.com/images/products/Gli1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-11109-img0002.jpg "Western Blot: GLI-1 Overexpression Lysate [NBL1-11109]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4E2 |
| Applications: | IHC, WB, KD |
