Fc gamma RIIIA/CD16a Products
Fc gamma RIIIA/CD16a is a low/intermediate affinity activating receptor for polyvalent immune-complexed IgG. It is involved in phagocytosis, secretion of enzymes and inflammatory mediators, antibody-dependent cytotoxicity, and clearance of immune complexes. It is expressed on NK cells, T cells, monocytes, and macrophages. It is closely related to the GPI-linked Fc gamma RIIIB which is expressed on neutrophils and eosinophils.
Surface expression requires interaction with an accessory chain, either the common gamma chain or CD3 zeta. Shed forms of both Fc gamma RIIIA and Fc gamma RIIIB can be generated by proteolytic cleavage and retain binding activity. Soluble Fc gamma RIII circulates in normal plasma and is elevated in rheumatoid arthritis and in coronary artery diseases.
Products:
245 results for "Fc gamma RIIIA/CD16a" in Products
245 results for "Fc gamma RIIIA/CD16a" in Products
Fc gamma RIIIA/CD16a Products
Fc gamma RIIIA/CD16a is a low/intermediate affinity activating receptor for polyvalent immune-complexed IgG. It is involved in phagocytosis, secretion of enzymes and inflammatory mediators, antibody-dependent cytotoxicity, and clearance of immune complexes. It is expressed on NK cells, T cells, monocytes, and macrophages. It is closely related to the GPI-linked Fc gamma RIIIB which is expressed on neutrophils and eosinophils.
Surface expression requires interaction with an accessory chain, either the common gamma chain or CD3 zeta. Shed forms of both Fc gamma RIIIA and Fc gamma RIIIB can be generated by proteolytic cleavage and retain binding activity. Soluble Fc gamma RIII circulates in normal plasma and is elevated in rheumatoid arthritis and in coronary artery diseases.
Products:
Analyzed by SEC-MALS, Isoform V176, His-tag
| Source: | NS0 |
| Accession #: | AAH17865 |
| Applications: | Bind |
Low-affinity V176F polymorphic variant
| Source: | HEK293 |
| Accession #: | P08637 |
| Applications: | BA |
| Reactivity: | Human, Primate |
| Details: | Mouse IgG1 kappa Monoclonal Clone #3G8 |
| Applications: | IHC, Flow, IP, CyTOF-ready |
Biotinylated Isoform V176
| Source: | HEK293 |
| Accession #: | AAH17865.1 |
| Applications: | BA, BA |
| Reactivity: | Human, Primate, Porcine |
| Details: | Mouse IgM Monoclonal Clone #MEM-168 |
| Applications: | Flow |
| Source: | NS0 |
| Accession #: | NP_997486 |
| Applications: | BA |
| Reactivity: | Human, Cynomolgus Monkey |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #DMC219 |
| Applications: | ELISA, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #DJ130c |
| Applications: | IHC, Flow |
Recombinant Monoclonal
| Reactivity: | Human |
| Details: | Rabbit Monoclonal Clone #BLR162J |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #2G10A9 |
| Applications: | WB, ELISA, Flow |
| Applications: | AC |
Recombinant monoclonal antibody expressed in HEK293F cells
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #25G6 |
| Applications: | ELISA, ICC/IF |
| Applications: | ELISA |
| Applications: | WB |
| Reactivity: | Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, IP |
| Reactivity: | Human, Primate |
| Details: | Mouse IgG1 kappa Monoclonal Clone #3G8 |
| Applications: | IHC, Flow, IP, CyTOF-ready |
| Reactivity: | Human, Primate |
| Details: | Mouse IgG1 kappa Monoclonal Clone #3G8 |
| Applications: | IHC, Flow, IP, CyTOF-ready |
| Applications: | WB |
| Reactivity: | Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, IP |
| Reactivity: | Human, Cynomolgus Monkey |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |
| Reactivity: | Human, Cynomolgus Monkey |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |
| Reactivity: | Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, IP |