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1 result for "FAK" in Products
FAK Products
FAK (Focal Adhesion Kinase) is a non-receptor protein tyrosine kinase involved in signal transduction from integrin-enriched focal adhesion sites that mediate cell contact with the extracellular matrix. FAK-enhanced signals have been shown to mediate the survival of anchorage-dependent cells and are critical for efficient cell migration in response to growth factor receptor and integrin stimulation. Elevated expression of FAK in human tumors has been correlated with increased malignancy and invasiveness.
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #495919
Applications:
KO, IHC, WB, Simple Western
