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18 results for "Endocan/ESM-1" in Products
Endocan/ESM-1 Products
Endocan, also known as Endothelial Cell-specific Molecule-1 (ESM-1) and IGFBP-rp6, is a secreted cysteine-rich dermatan sulfate proteoglycan. It is primarily expressed by endothelial cells within the vascular network of the kidney and in the alveolar walls of the lung. Endocan expression is upregulated by TNF-alpha, IL-1 beta and LPS, and downregulated by IFN-gamma. Endocan binds LFA-1 on human lymphocytes, monocytes and Jurkat cells, inhibiting its binding to ICAM-1 and reducing LFA-1-mediated leukocyte activation. Elevated circulating Endocan levels have been reported in patients with lung cancer and severe sepsis.
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
IHC, WB
Reactivity:
Human
Source:
NS0
Accession #:
Q9NQ30
Applications:
Bioactivity
Reactivity:
Human
Details:
Mouse IgG2b Kappa Monoclonal Clone #6D4
Applications:
IHC, WB, ELISA, ICC/IF
Reactivity:
Human
Assay Range:
15.63-1000 pg/mL
Applications:
ELISA
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, B/N
Reactivity:
Mouse
Source:
NS0
Accession #:
Q9QYY7
Applications:
Bioactivity
Reactivity:
Mouse
Details:
Rat IgG2B Monoclonal Clone #220008
Applications:
WB, ELISA(Cap)
Reactivity:
Human
Reactivity:
Rat
Assay Range:
78.13 - 5000 pg/mL
Applications:
ELISA
Reactivity:
Human
Assay Range:
7.81-500 pg/mL
Applications:
ELISA
Reactivity:
Mouse
Reactivity:
Human
Applications:
WB
Reactivity:
Human
Details:
Mouse IgG1 kappa Monoclonal Clone #C7
Applications:
WB
Reactivity:
Human
Reactivity:
Mouse
Details:
Rat IgG2 Monoclonal Clone #RM0079-5J44
Applications:
WB
Reactivity:
Human
Details:
Mouse IgG1 kappa Monoclonal Clone #E1
Applications:
ELISA
Reactivity:
Rat