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1 result for "CTLA-4 Simple Plex" in Products
CTLA-4 Simple Plex
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
Catalog #:
898485
Control for use with Human and Non-Human Primate CTLA-4 Simple Plex Cartridge Kit
Reactivity:
Human, Non-human Primate
Applications:
Ctrl, Simple Plex