CTLA-4: Proteins and Enzymes
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
7 results for "CTLA-4 Proteins and Enzymes" in Products
7 results for "CTLA-4 Proteins and Enzymes" in Products
CTLA-4: Proteins and Enzymes
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
| Source: | Sf 21 (baculovirus) |
| Accession #: | Q6GR94 |
| Applications: | BA |
| Source: | CHO |
| Accession #: | P16410 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | Q6GTR6 |
| Applications: | BA |
| Source: | HEK293 |
| Accession #: | P16410.3 |
| Applications: | BA |
| Source: | HEK293 |
| Accession #: | XP_005574071 |
| Applications: | BA |
| Source: | CHO |
| Accession #: | NP_001003106.1 |
| Applications: | BA |
![SDS-PAGE: Recombinant Human CTLA-4 His Protein [NBP2-22987]](https://resources.bio-techne.com/images/products/CTLA4-Protein-SDS-Page-NBP2-22987-img0001.jpg "SDS-PAGE: Recombinant Human CTLA-4 His Protein [NBP2-22987]")