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7 results for "CTLA-4 ELISA Kits" in Products
CTLA-4 ELISA Kits
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
Reactivity:
Human
Assay Range:
0.781-50 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Urine)
Applications:
ELISA
Reactivity:
Mouse
Assay Range:
125-8000 pg/mL
Applications:
ELISA
For use with catalog number HSCT40
Reactivity:
Human
Applications:
Ctrl
Reactivity:
Rat
Assay Range:
0.16 - 10 ng/mL
Applications:
ELISA
Reactivity:
Mouse
Assay Range:
125 - 8000 pg/mL
Applications:
ELISA
Reactivity:
Human
Assay Range:
70.31-4500 pg/ml (example only; lot dependent)
Applications:
ELISA
Reactivity:
Human
Assay Range:
70.31-4500 pg/ml (example only; lot dependent)
Applications:
ELISA