4 results for "CDK8 Small Molecules and Peptides" in Products
CDK8: Small Molecules and Peptides
Cdk8 is encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. ...
Potent and selective CDK8 and CDK19 inhibitor; maintains pluripotency of mouse PSCs in culture
| Chemical Name: | N-Propyl-3-(4-pyridinyl)imidazo[1,2-b]pyridazin-6-amine |
| Purity: | ≥98% (HPLC) |
Cdk8 inhibitor
| Chemical Name: | 4-[(2-Phenylethyl)amino]-6-quinazolinecarbonitrile hydrochloride |
| Purity: | ≥98% (HPLC) |
CDK8 Degrader (PROTAC®)
| Chemical Name: | 15-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-N-[(3β,5α,17β)-17-(7-isoquinolinyl)androstan-3-yl]-N-methyl-4,7,10,13-tetraoxapentadecanamide |
| Purity: | ≥98% (HPLC) |
Cdk inhibitor; potently inhibits cdk2 and cdk9
| Alternate Names: | L 86-8275 |
| Chemical Name: | 2-(2-Chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4H-1-benzopyran-4-one hydrochloride |
| Purity: | ≥98% (HPLC) |
