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11 results for "CD25/IL-2R alpha Proteins and Enzymes" in Products
CD25/IL-2R alpha Proteins and Enzymes
CD25/IL-2 receptor alpha is a transmembrane protein that associates with IL-2R beta/CD122 and the Common gamma Chain/CD132 on activated T cells and regulatory T cells (Treg). The Common gamma chain is a shared subunit in the receptors for IL-4, -7, -9, -15, and -21. IL-2R alpha is required for mediating IL-2 induced effects including T cell proliferation, activation induced cell death (AICD) of autoreactive naive T cells, and the development of CD4+CD25+ Treg which contribute to peripheral T cell homeostasis. A soluble form of IL-2R alpha can be generated by proteolytic cleavage of the cell surface receptor.
Reactivity:
Human
Source:
HEK293
Accession #:
P01589
Applications:
Bioactivity
Reactivity:
Human
Source:
NS0
Accession #:
P01589
Applications:
Bioactivity
Reactivity:
Human
Source:
NS0
Accession #:
Q5W007
Applications:
Bioactivity
Reactivity:
Cynomolgus Monkey
Source:
HEK293
Accession #:
NP_001270633.1
Applications:
Bioactivity
Reactivity:
Cynomolgus Monkey
Source:
HEK293
Accession #:
NP_001270633.1
Applications:
Bioactivity
Reactivity:
Canine
Source:
NS0
Accession #:
BAI49682
Applications:
Bioactivity
Biotinylated
Reactivity:
Human
Source:
HEK293
Accession #:
P01589.1
Applications:
Binding Activity, Bioactivity
Reactivity:
Mouse
Source:
NS0
Accession #:
Q544I2
Applications:
Bioactivity
Reactivity:
Rat
Source:
CHO
Accession #:
P26897
Applications:
Bioactivity
Biotinylated
Reactivity:
Human
Source:
HEK293
Accession #:
P01589.1
Applications:
Bioactivity
Biotinylated
Reactivity:
Human
Source:
HEK293
Accession #:
P01589.1
Applications:
Bioactivity