CD11c Products

CD11c, also known as the Integrin alpha X subunit, is a 150 kDa type I transmembrane protein that noncovalently heterodimerizes with the Integrin beta 2 subunit (CD18). This heterodimeric protein (Integrin alpha X beta 2) is also known as p150/p95 and complement receptor type 4 (CR4). Integrin alpha X beta 2 is expressed on macrophages, dendritic cells, hairy cell leukemias, and some other leukocyte subsets. aXb2 shares some adhesion partners with aMb2 including Complement iC3b, ICAMs, vWF, and ...