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2 results for "CD117/c-kit" in Products

CD117/c-kit Products

CD117, also known as c-kit and SCF R, is the cellular receptor for Stem Cell Factor (SCF), also named c-kit ligand, mast cell growth factor, and steel factor. This receptor-ligand system plays essential roles in germ cell development, melanogenesis, hematopoiesis, and oncogenesis. CD117 is expressed on lymphoid, myeloid,  erythroid, and megakaryocyte progenitors, NK cells, germ cells, melanocytes, glial cells, vascular smooth muscle cells, placenta, and epithelial cells. Altered levels and mutations in CD117 are associated with several types of cancer including lung, breast, gastrointestinal stromal, and germ cell tumors.

Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #47233
Applications:
Flow
Detection of CD117/c-kit antibody in TF‑1 Human Cell Line antibody by Flow Cytometry.
Reactivity:
Mouse
Details:
Rat IgG2A Monoclonal Clone #180627
Applications:
Flow
Detection of CD117/c-kit antibody in Mouse Splenoctyes antibody by Flow Cytometry.
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