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CCL3/MIP-1 alpha: Simple Plex

CCL3/MIP-1 alpha, is a beta chemokine that can be induced in a variety of hematopoietic cells, fibroblasts, smooth muscle cells, and epithelial cells. It forms complexes with sulfated proteoglycans and also associates into noncovalently-linked dimers and high molecular weight polymers. These complexes of CCL3 are protected from proteolytic digestion by insulin degrading enzyme (IDE) which can cleave the monomeric chemokine. CCL3 signals through CCR1, CCR3, and CCR5, and it is internalized by the decoy chemokine receptor D6. CCL3 promotes the chemoattraction, adhesion to activated vascular endothelium, and cellular activation of many hematopoietic cell types. It can promote tumor metastasis, hyperalgesia, and inflammation and suppress HIV replication and hematopoietic stem cell proliferation.

6 results for "CCL3/MIP-1 alpha Simple Plex" in Products

CCL3/MIP-1 alpha: Simple Plex

CCL3/MIP-1 alpha, is a beta chemokine that can be induced in a variety of hematopoietic cells, fibroblasts, smooth muscle cells, and epithelial cells. It forms complexes with sulfated proteoglycans and also associates into noncovalently-linked dimers and high molecular weight polymers. These complexes of CCL3 are protected from proteolytic digestion by insulin degrading enzyme (IDE) which can cleave the monomeric chemokine. CCL3 signals through CCR1, CCR3, and CCR5, and it is internalized by the decoy chemokine receptor D6. CCL3 promotes the chemoattraction, adhesion to activated vascular endothelium, and cellular activation of many hematopoietic cell types. It can promote tumor metastasis, hyperalgesia, and inflammation and suppress HIV replication and hematopoietic stem cell proliferation.

6 results for "CCL3/MIP-1 alpha Simple Plex" in Products

Simple Plex Human CCL3/MIP-1 alpha assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Catalog #: 898059

Control for use with Human CCL3/MIP-1 alpha Simple Plex Cartridge Kit

Simple Plex Mouse CCL3/MIP-1 alpha assay kit for use on Ella instrument. Contains cartridge, sample diluent SD09, and wash buffer.

Catalog #: 897072

Control for use with Mouse G-CSF Simple Plex Assay Cartridge Kit

Catalog #: 897061

Control for use with Mouse CCL3 Simple Plex Assay Cartridge Kit

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