Carboxylesterase 2/CES2: Proteins and Enzymes

Carboxylesterase 2 (CES2) is a member of a large family of carboxylesterases that are responsible for the hydrolysis of ester and amide bonds. They have broad substrate specificity ranging from small molecule esters such as phenylester to long-chain fatty acid esters and thioesters. Carboxylesterases play a major role as determinants of pharmacokinetic behavior for most therapeutic agents containing an ester, participating in the detoxification of drugs such as cocaine and heroin in serum and ...