BMP-15/GDF-9B Products
BMP-15 (Bone morphogenetic protein 15), also known as GDF-9B, is a TGF-b superfamily ligand that is expressed by oocytes throughout folliculogenesis and plays an important role in oocyte development. BMP-15 promotes the FSH-independent proliferation of ovarian granulosa cells (GC) and induces GC glycolysis and cholesterol synthesis.
BMP-15 blocks the FSH-induced GC expression of FSH R and multiple steroidogenic molecules. BMP-15 exerts is effects through interactions with BMPR-IB/ALK6 and BMPR-II, and nonphosphorylated BMP-15 functions as a competitive antagonist at BMPR-IB. Mature BMP-15 forms 34 kDa noncovalently-linked homodimers and 37 kDa heterodimers with mature GDF-9.
Products:
193 results for "BMP-15/GDF-9B" in Products
193 results for "BMP-15/GDF-9B" in Products
BMP-15/GDF-9B Products
BMP-15 (Bone morphogenetic protein 15), also known as GDF-9B, is a TGF-b superfamily ligand that is expressed by oocytes throughout folliculogenesis and plays an important role in oocyte development. BMP-15 promotes the FSH-independent proliferation of ovarian granulosa cells (GC) and induces GC glycolysis and cholesterol synthesis.
BMP-15 blocks the FSH-induced GC expression of FSH R and multiple steroidogenic molecules. BMP-15 exerts is effects through interactions with BMPR-IB/ALK6 and BMPR-II, and nonphosphorylated BMP-15 functions as a competitive antagonist at BMPR-IB. Mature BMP-15 forms 34 kDa noncovalently-linked homodimers and 37 kDa heterodimers with mature GDF-9.
Products:
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #BMP15/4263 |
| Applications: | WB, ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #BMP15/4263 |
| Applications: | WB, ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #BMP15/4263 |
| Applications: | WB, ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #BMP15/4263 |
| Applications: | WB, ELISA |
| Source: | CHO |
| Accession #: | O95972 |
| Applications: | BA |
| Reactivity: | Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #317809 |
| Applications: | WB, IHC |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #582703 |
| Applications: | IHC |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #317809 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #317809 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #317809 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #317809 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #317809 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #317809 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #317809 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #317809 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |