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202 results for "BACE-2" in Products
BACE-2 Products
Both BACE-1 and BACE-2 are membrane-bound aspartic proteases of the pepsin family. BACE-1 is a potential target for treatment of Alzheimer's disease because it is the principle b-secretase responsible for cleavage of amyloid precursor protein (APP). BACE-2 differs from BACE-1 in several aspects including pro-enzyme activation, substrate binding sites, transcriptional regulation, and function in A beta peptide production.
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, ICC/IF
![Western Blot: BACE-2 Antibody [NBP2-15539]](https://resources.rndsystems.com/images/products/BACE2-Antibody-Western-Blot-NBP2-15539-img0001.jpg "Western Blot: BACE-2 Antibody [NBP2-15539]")
Reactivity:
Human
Details:
Sheep IgG Polyclonal
Applications:
WB
Catalog #:
AF2977
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
WB, IP
Reactivity:
Mouse
Source:
NS0
Accession #:
Q9JL18
Applications:
Enzyme Activity
Reactivity:
Human
Details:
Sheep IgG Polyclonal
Applications:
WB, IP
Reactivity:
Human
Details:
Rat IgG2A Monoclonal Clone #391017
Applications:
IHC
Reactivity:
Human
Source:
NS0
Accession #:
Q9Y5Z0-1
Applications:
Enzyme Activity
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, ELISA
![Western Blot: BACE-2 AntibodyBSA Free [NBP1-77309]](https://resources.rndsystems.com/images/products/BACE-2-Antibody-Western-Blot-NBP1-77309-img0002.jpg "Western Blot: BACE-2 AntibodyBSA Free [NBP1-77309]")
Reactivity:
Human
Assay Range:
0.16 - 10 ng/mL
Applications:
ELISA
Reactivity:
Mouse
Reactivity:
Human
Potent and selective β-secretase (BACE) inhibitor
Chemical Name:
N-[3-[(4aS,7aS)-2-Amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide hydrochloride
Purity:
≥98%
Highly potent γ-secretase inhibitor; orally bioavailable
Alternate Names:
BMS-708163
Chemical Name:
(2R)-2-[[(4-Chlorophenyl)sulfonyl][[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoropentanamide
Purity:
≥98%
Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, ELISA
![Western Blot: BACE-2 AntibodyBSA Free [NBP1-77308]](https://resources.rndsystems.com/images/products/BACE-2-Antibody-Western-Blot-NBP1-77308-img0004.jpg "Western Blot: BACE-2 AntibodyBSA Free [NBP1-77308]")
Recombinant Monoclonal Antibody
Reactivity:
Human
Details:
Mouse IgG1 kappa Monoclonal Clone #1/ 9
Applications:
IHC, WB, ICC/IF
Reactivity:
Rat
Assay Range:
3.13 - 200 ng/mL
Applications:
ELISA
Catalog #:
AF2977G
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
WB, IP
Catalog #:
AF2977N
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
WB, IP
Catalog #:
AF2977R
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
WB, IP
Catalog #:
AF2977S
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
WB, IP
Catalog #:
AF2977T
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
WB, IP
Catalog #:
AF2977U
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
WB, IP
Catalog #:
AF2977V
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
WB, IP
Catalog #:
AF2977X
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
WB, IP
Catalog #:
AF4097G
Reactivity:
Human
Details:
Sheep IgG Polyclonal
Applications:
WB, IP