ATG7 Products

Autophagy Related 7 (ATG7), also known as APG7-like Gene (APG7L), is a 703 amino acid (aa) noncanonical member of the Ubiquitin-activating (E1) enzyme family with a predicted molecular weight of 78 kDa. The mouse and rat ATG7 orthologs share 93% aa sequence identity with the human protein. While ATG7 lacks a Ubiquitin fold domain, it contains a conserved metal binding domain, an active site cysteine residue, Cys572 in humans, and an ATP-binding domain common to E1 enzyme family members. ATG7 is ...