Complex, highly heterogeneous tissues, such as the brain, are comprised of multiple cell types and states. However, interrogation of these complex tissue types requires a highly sensitive, specific, and multiplexed spatial approach with single cell resolution. With the RNAscope technology, researchers can:
- Visualize the cellular heterogeneity of complex organs with the multiplexing and spatial capabilities of the RNAscope Multiplex Fluorescent and HiPlex assays
- Detect up to 12 RNA targets simultaneously in the tissue context with the RNAscope HiPlex assay
- Spatially map scRNA-seq gene profiles at the single cell level in the tissue context
- Localize newly identified cell subtypes and cell markers
- Confirm scRNA-seq results from publicly available datasets in the tissue context
- Combine the RNAscope Multiplex Fluorescent Assays with IHC/ IF to simultaneously detect RNA and protein
