HaXS8

Tocris Bioscience, part of Bio-Techne | Catalog # 4991

Chemical dimerizer
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Key Product Details

Description

Chemical dimerizer

View all Protein Dimerizers Supplemental Kits and Reagents »

Product Description

HaXS8 is a chemical dimerizer that promotes covalent and irreversible HaloTag® and SNAP-tag® substrate dimerization. Cell permeable.

HaloTag is a trademark of Promega Corporation, and SNAP-tag is a trademark of New England BioLabs, Inc.

Product Specifications

Molecular Weight

787.20

Formula

C35H43ClF4N6O8

Storage

Store at -20°C

Purity

≥90% (HPLC)

Chemical Name

N-[[4-[[(2-Amino-9-H-purin-6-yl)oxy]methyl]phenyl]methyl]-2-[4-[(18-chloro-3,6,9,12-tetraoxaoctadec-1yl)oxy]-2,3,5,6-tetrafluorophenoxy]acetamide

CAS Number

2080306-25-6

PubChem ID

124201846

InChI Key

OHHUCZCSUXJJFO-UHFFFAOYSA-N

SMILES

NC1=NC2=C(N=CN2)C(OCC3=CC=C(CNC(COC4=C(F)C(F)=C(OCCOCCOCCOCCOCCCCCCCl)C(F)=C4F)=O)C=C3)=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 78.72 100

Preparing Stock Solutions for HaXS8

The following data is based on the product molecular weight 787.20

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.27 mL 6.35 mL 12.70 mL
5 mM 0.25 mL 1.27 mL 2.54 mL
10 mM 0.13 mL 0.64 mL 1.27 mL
50 mM 0.03 mL 0.13 mL 0.25 mL

Calculators

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

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Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background References

References are publications that support the biological activity of the product.

Product Documents for HaXS8

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for HaXS8

For research use only

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