β-Cyclodextrin
Tocris Bioscience, part of Bio-Techne | Catalog # 3181
Cyclic complexing agent
Key Product Details
Description
Cyclic complexing agent
Product Description
β-Cyclodextrin (β-CD) is a cyclic oligosaccharide comprising seven glucose subunits linked by α-1,4-glycosidic bonds, forming a cage-like supramolecular structure with a hydrophobic interior and a hydrophilic exterior. β-Cyclodextrins can form inclusion complexes with a diverse range of hydrophobic compounds. These complexes increase the aqueous solubility, dissolution rate, and bioavailability of the guest compounds.Product Specifications
Molecular Weight
1134.99
Formula
C42H70O35
Storage
Store at RT
Purity
≥98% (HPLC)
CAS Number
7585-39-9
InChI Key
WHGYBXFWUBPSRW-FOUAGVGXSA-N
SMILES
O[C@@H]1[C@@H](O)[C@H](O[C@@H]2[C@H](O)[C@@H](O)[C@H](O3)[C@@H](CO)O2)[C@@H](CO)O[C@@H]1O[C@H]4[C@H](O)[C@@H](O)[C@@H](O[C@H]5[C@H](O)[C@@H](O)[C@@H](O[C@H]6[C@H](O)[C@@H](O)[C@@H](O[C@H]7[C@H](O)[C@@H](O)[C@@H](O[C@H]8[C@H](O)[C@@H](O)[C@@H]3O[C@@H]8CO)O[C@@H]7CO)O[C@@H]6CO)O[C@@H]5CO)O[C@@H]4CO
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 11.35 | 10 | |
| DMSO | 113.5 | 100 |
Preparing Stock Solutions
for β-Cyclodextrin
The following data is based on the product molecular weight 1134.99
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 0.88 mL | 4.41 mL | 8.81 mL |
| 5 mM | 0.18 mL | 0.88 mL | 1.76 mL |
| 10 mM | 0.09 mL | 0.44 mL | 0.88 mL |
| 50 mM | 0.02 mL | 0.09 mL | 0.18 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Armstrong Separation of drug stereoisomers by the formation of beta-cyclodextrin inclusion complexes. Science 1986 PMID: 3704640
Product Specific Notices for β-Cyclodextrin
For research use only
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