SenTraGor™
Tocris Bioscience, part of Bio-Techne | Catalog # 7555
Reagent for staining and detection of lipofuscin in senescent cells
Key Product Details
Description
Reagent for staining and detection of lipofuscin in senescent cells
Product Description
SenTraGor™ is a reagent for detecting lipofuscin in senescent cells. A highly lipophilic and biotinylated analog of Sudan Black B; can be detected using an anti-biotin antibody. Can be used in vivo and in vitro in any biological material including cell cultures, fresh and frozen tissues, and fixed embedded samples. Compatible with immunohistochemistry, flow cytometry and immunofluorescence analysis.SenTraGor™ is a trademark of University of Manchester.
Licensing Information
Sold under license from University of Manchester Innovation FactoryProduct Specifications
Molecular Weight
698.85
Formula
C39H38N8O3S
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
(2-Methyl-6-((E)-(4-((E)-phenyldiazenyl)naphthalen-1-yl)diazenyl)-2,3-dihydro-1H-perimidin-2-yl)methyl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate
CAS Number
2171036-89-6
PubChem ID
166603878
InChI Key
NCGWNTJOKSLKQK-SPNFGPMXSA-N
SMILES
[H][C@]12CS[C@H]([C@]1(NC(N2)=O)[H])CCCCC(OCC3(C)NC4=CC=CC5=C4C(N3)=CC=C5/N=N/C6=CC=C(C7=C6C=CC=C7)/N=N/C8=CC=CC=C8)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 13.98 | 20 | |
| Ethanol | 6.99 | 10 with gentle warming |
Preparing Stock Solutions
for SenTraGor™
The following data is based on the product molecular weight 698.85
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.2 mM | 7.15 mL | 35.77 mL | 71.55 mL |
| 1 mM | 1.43 mL | 7.15 mL | 14.31 mL |
| 2 mM | 0.72 mL | 3.58 mL | 7.15 mL |
| 10 mM | 0.14 mL | 0.72 mL | 1.43 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Evangelou Robust, universal biomarker assay to detect senescent cells in biological specimens Aging Cell 2017 PMID: 28165661
Product Specific Notices for SenTraGor™
For research use only
Loading...
Loading...