Pimonidazole
Tocris Bioscience, part of Bio-Techne | Catalog # 6182
Hypoxia detection reagent
Key Product Details
Description
Hypoxia detection reagent
Product Description
Pimonidazole is a hypoxia detection reagent. Labels hypoxic tumor cells in vivo. Also labels hypoxic mesenchymal stem cells in mouse bone marrow.Product Specifications
Molecular Weight
254.29
Formula
C11H18N4O3
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
α-[(2-Nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol
CAS Number
70132-50-2
PubChem ID
50981
InChI Key
WVWOOAYQYLJEFD-UHFFFAOYSA-N
SMILES
OC(CN1CCCCC1)CN2C=CN=C2[N+]([O-])=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 25.43 | 100 | |
| Ethanol | 25.43 | 100 |
Preparing Stock Solutions
for Pimonidazole
The following data is based on the product molecular weight 254.29
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.93 mL | 19.66 mL | 39.33 mL |
| 5 mM | 0.79 mL | 3.93 mL | 7.87 mL |
| 10 mM | 0.39 mL | 1.97 mL | 3.93 mL |
| 50 mM | 0.08 mL | 0.39 mL | 0.79 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Bennewith Orally administered pimonidazole to label hypoxic tumor cells. Cancer Res. 2002 PMID: 12460894
- Sato Notch2 signaling regulates the proliferation of murine bone marrow-derived mesenchymal stem/stromal cells via c-Myc expression. PLoS One 2016 PMID: 27855169
Product Specific Notices for Pimonidazole
For research use only
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