Zolantidine dimaleate
Tocris Bioscience, part of Bio-Techne | Catalog # 1070
Potent, centrally active H2 antagonist
Key Product Details
Description
Potent, centrally active H2 antagonist
Product Description
Zolantidine dimaleate is a a potent, selective and brain penetrating H2 receptor antagonist.Licensing Information
Sold with the permission of GlaxoSmithKlineProduct Specifications
Molecular Weight
613.68
Formula
C22H27N3OS.2C4H4O4
Storage
Desiccate at +4°C
Chemical Name
N-[3-[3-(1-Piperidinylmethyl)phenoxy]propyl]-2-benzothiazolamine dimaleate
CAS Number
104076-39-3
PubChem ID
11957725
InChI Key
IECBEVAUEBZJCF-SPIKMXEPSA-N
SMILES
OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.C(CNC1=NC2=C(S1)C=CC=C2)COC1=CC(CN2CCCCC2)=CC=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 100 |
Preparing Stock Solutions
for Zolantidine dimaleate
The following data is based on the product molecular weight 613.68
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.63 mL | 8.15 mL | 16.30 mL |
| 5 mM | 0.33 mL | 1.63 mL | 3.26 mL |
| 10 mM | 0.16 mL | 0.81 mL | 1.63 mL |
| 50 mM | 0.03 mL | 0.16 mL | 0.33 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Coruzzi Activity of the new histamine H2-receptor antagonist zolantidine at cardiac and gastric H2 receptors. Pharmacology 1994 PMID: 7907797
- Coruzzi Cardiac and gastric effects of histamine H2 receptor antagonists: no evidence for a correlation between lipophilicity and receptor affinity. Br.J.Pharmacol. 1996 PMID: 8842448
- Calcutt Zolantidine (SK&F 95282) is a potent selective brain penetrating histamine H2-receptor antagonist. Br.J.Pharmacol. 1988 PMID: 2894879
Product Specific Notices for Zolantidine dimaleate
For research use only
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