XIAP Tracer mF-Smac
Tocris Bioscience, part of Bio-Techne | Catalog # 8069
Fluorescein labeled XIAP ligand for TR-FRET assay development
Key Product Details
Description
Fluorescein labeled XIAP ligand for TR-FRET assay development
Product Description
XIAP Tracer mF-Smac is a fluorescent labeled peptide used as an acceptor dye with a terbium labeled BIR domain antibody in TR-FRET assays (Kd values are 4.7 nM at BIR3 (XIAP); 17.9 nM in XIAP polarization assay).Optical Data
| Emission Color | Near-IR |
| λabs | 485 nm |
| λem | 520 nm |
| Closest Laser line | 488 nm |
| Application | Fluorescence polarization (FP), Time-resolved fluorescence energy transfer (TR-FRET) |
Product Specifications
Molecular Weight
989.10
Formula
C51H60N10O11
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
783340-88-5
InChI Key
ONHYLEJPWIONKB-HECCNADXSA-N
SMILES
CC[C@H](N)C(N[C@H](C(N1CCC[C@H]1C(N[C@H](C(N[C@H](C(N)=O)CCCCNC(C2=CC=C3C(C(OC34C5=CC=C(O)C=C5OC6=CC(O)=CC=C64)=O)=C2)=O)=O)CC7=CC=CC=C7)=O)=O)CCCNC(N)=N)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 2mg/ml in 25% ethanol / water |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Chaudhry Building homogeneous time-resolved fluorescence resonance energy transfer assays for characterization of bivalent inhibitors of an inhibitor of apoptosis protein target. Anal.Biochem. 2016 PMID: 26743718
Product Specific Notices for XIAP Tracer mF-Smac
For research use only
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