WM 3835
Tocris Bioscience, part of Bio-Techne | Catalog # 7366
Lysine acetyltransferase HBO1 (KAT7) inhibitor
Key Product Details
Description
Lysine acetyltransferase HBO1 (KAT7) inhibitor
Product Description
WM 3835 is a lysine acetyltransferase HBO1 (KAT7) inhibitor. Reduces H3K14ac levels and inhibits growth and viability of acute myeloid leukemia cell lines in vitro. Cell-permeable.Product Specifications
Molecular Weight
400.42
Formula
C20H17FN2O4S
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
N'-(4-Fluoro-5-methyl-[1,1'-biphenyl]-3-carbonyl)-3-hydroxybenzenesulfonohydrazide
CAS Number
2229025-70-9
PubChem ID
134581412
InChI Key
KVJFJJXCBRSCDY-UHFFFAOYSA-N
SMILES
CC1=CC(C2=CC=CC=C2)=CC(C(NNS(=O)(C3=CC(O)=CC=C3)=O)=O)=C1F
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 40.04 | 100 | |
| Ethanol | 20.02 | 50 |
Preparing Stock Solutions
for WM 3835
The following data is based on the product molecular weight 400.42
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.50 mL | 12.49 mL | 24.97 mL |
| 5 mM | 0.50 mL | 2.50 mL | 4.99 mL |
| 10 mM | 0.25 mL | 1.25 mL | 2.50 mL |
| 50 mM | 0.05 mL | 0.25 mL | 0.50 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- MacPherson HBO1 is required for the maintenance of leukaemia stem cells. Nature 2019 PMID: 31827282
Product Specific Notices for WM 3835
For research use only
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