WAY 200070

Name: WAY 200070
Brand: Tocris Bioscience
SKU: 3366

Tocris Bioscience, part of Bio-Techne | Catalog # 3366

Citations (22)

COA / SDS

Selective ERβ agonist

Discontinued Product

3366 has been discontinued. View all Estrogen and Related Receptor Agonists products.

Key Product Details

Description:	Selective ERβ agonist
Chemical Name:	7-Bromo-2-(4-hydroxyphenyl)-1,3-benzoxazol-5-ol
Purity:	≥98% (HPLC)
Molecular Weight:	306.11

View Full Technical Details for WAY 200070

Technical Data
Citations

Biological Activity for WAY 200070

WAY 200070 is a selective ERβ receptor agonist that displays 68-fold selectivity over ERα (EC₅₀ values are 2 and 155 nM for ERβ and ERα respectively). Displays antianxiolytic and antidepressive effects in vivo.

Technical Data for WAY 200070

M. Wt	306.11
Formula	C₁₃H₈BrNO₃
Storage	Store at RT
Purity	≥98% (HPLC)
CAS Number	440122-66-7
PubChem ID	9861330
InChi Key	IVFWABSHZFOMIG-UHFFFAOYSA-N
Smiles	BrC1=C2C(N=C(C3=CC=C(O)C=C3)O2)=CC(O)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for WAY 200070

References are publications that support the biological activity of the product.

Hughes WAY-200070, a selective agonist of estrogen receptor beta as a potential novel anxiolytic/antidepressant agent. Neuropharmacology 2008 PMID: 18423777
Clipperton Differential effects of estrogen receptor alpha and beta specific agonists on social learning of food preferences in female mice. Neuropsychopharmacology 2008 PMID: 18004284
Malamas Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-β ligands. J.Med.Chem. 2004 PMID: 15456246

WAY 200070

Tocris Bioscience, part of Bio-Techne | Catalog # 3366

Key Product Details

Biological Activity for WAY 200070

Technical Data for WAY 200070

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for WAY 200070

Product Documents for WAY 200070

COA

Certificate of Analysis

SDS

CONTACT INFORMATION

保持关注