VU 0238429

Tocris Bioscience, part of Bio-Techne | Catalog # 3634

Selective positive allosteric modulator of M5 receptors
Discontinued Product
3634 has been discontinued. View all mAChR M5 Modulators products.

Key Product Details

Description

Selective positive allosteric modulator of M5 receptors

View all mAChR M5 Modulators »

Product Description

VU 0238429 is a selective positive allosteric modulator of M5 receptors (EC50 values are 1.16, >30 and >30 μM at M5, M1 and M3 receptors respectively). Displays no activity at M2 and M4 receptors.

Product Specifications

Molecular Weight

351.28

Formula

C17H12F3NO4

Storage

Store at -20°C

Purity

≥97% (HPLC)

Chemical Name

1-(4-Methoxybenzyl)-5-trifluoromethoxyisatin

CAS Number

1160247-92-6

PubChem ID

42633508

InChI Key

CKLGZXFOLMHCMC-UHFFFAOYSA-N

SMILES

O=C(C1=CC(OC(F)(F)F)=CC=C1N2CC3=CC=C(OC)C=C3)C2=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 35.13 100

Preparing Stock Solutions for VU 0238429

The following data is based on the product molecular weight 351.28

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.85 mL 14.23 mL 28.47 mL
5 mM 0.57 mL 2.85 mL 5.69 mL
10 mM 0.28 mL 1.42 mL 2.85 mL
50 mM 0.06 mL 0.28 mL 0.57 mL

Calculators

Molarity Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for VU 0238429

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for VU 0238429

For research use only

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