Voglibose

Name: Voglibose
Brand: Tocris Bioscience
SKU: 3596

Tocris Bioscience, part of Bio-Techne | Catalog # 3596

COA / SDS

Orally active α-glucosidase inhibitor

Discontinued Product

3596 has been discontinued. View all Glycosylase Inhibitors products.

Key Product Details

Description:	Orally active α-glucosidase inhibitor
Chemical Name:	3,4-Dideoxy-4-[[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-2-C-(hydroxymethyl)-D-epi-inositol
Molecular Weight:	267.28

View Full Technical Details for Voglibose

Technical Data
Citations

Biological Activity for Voglibose

Voglibose is an orally active α-glucosidase inhibitor (IC₅₀ values are 3.9 and 6.4 nM at sucrase and maltase respectively). Increases glucagon-like peptide 1 (GLP-1) secretion and decreases food consumption in ob/ob mice, and reduces plasma concentrations of glucose, triglycerides and insulin in Wistar fatty rats. Exhibits antidiabetic and antiobesity activity in vivo.

Technical Data for Voglibose

M. Wt	267.28
Formula	C₁₀H₂₁NO₇
Storage	Store at -20°C
CAS Number	83480-29-9
PubChem ID	444020
InChi Key	FZNCGRZWXLXZSZ-CIQUZCHMSA-N
Smiles	O[C@@H]1[C@](CO)(O)C[C@H](NC(CO)CO)[C@H](O)[C@H]1O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Voglibose

References are publications that support the biological activity of the product.

Matsui α-Glucosidase inhibition assay in an enzyme-immobilized amino-microplate. Anal.Sci. 2009 PMID: 19359799
Moritoh Chronic administration of voglibose, an α-glucosidase inhibitor, increases active glucagon-like peptide-1 levels by increasing its secretion and decreasing dipeptidyl peptidase-4 activity in ob/ob mice. J.Pharmacol.Exp.Ther. 2009 PMID: 19208898
Matsuo Effect of an intestinal disaccharidase inhibitor (AO-128) on obesity and diabetes. Am.J.Clin.Nutr. 1992 PMID: 1728846

Voglibose

Tocris Bioscience, part of Bio-Techne | Catalog # 3596

Key Product Details

Biological Activity for Voglibose

Technical Data for Voglibose

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Voglibose

Product Documents for Voglibose

COA

Certificate of Analysis

SDS

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