Urotensin II (human)

Name: Urotensin II (human)
Brand: Tocris Bioscience
SKU: 1642

Tocris Bioscience, part of Bio-Techne | Catalog # 1642

COA / SDS

Endogenous vasoactive agonist for the UT receptor

Discontinued Product

1642 has been discontinued. View all Urotensin-II Receptor Agonists products.

Key Product Details

Description:	Endogenous vasoactive agonist for the UT receptor
Molecular Weight:	1388.57

View Full Technical Details for Urotensin II (human)

Technical Data
Citations

Biological Activity for Urotensin II (human)

Urotensin II (human) is a potent endogenous peptide agonist for the urotensin-II receptor (EC₅₀ = 0.1 nM). Displays arterio-selective vasoconstriction and vasodilatation in mammals in vitro and in vivo, effects which vary between species. Also has been shown to mediate bronchoconstriction.

Technical Data for Urotensin II (human)

M. Wt	1388.57
Formula	C₆₄H₈₅N₁₃O₁₈S₂
Single Letter Sequence	ETPDCFWKYCV (Modifications: Disulfide bridge between 5 - 10)
Storage	Desiccate at -20°C
CAS Number	251293-28-4
PubChem ID	46225600
InChi Key	HFNHAPQMXICKCF-USJMABIRSA-N
Smiles	[H]N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CC2=CC=CC=C2)NC1=O)C(=O)N[C@@H](C(C)C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for Urotensin II (human)

References are publications that support the biological activity of the product.

Maguire and Davenport Is urotensin-II the new endothelin? Br.J.Pharmacol 2002 PMID: 12381671
Nothacker Identification of the natural ligand of an orphan G-protein-coupled receptor involved in the regulation of vasoconstriction. Nat.Cell.Biol. 1999 PMID: 10559967
Coulouarn Cloning of the cDNA encoding the urotensin II precursor in frog and human reveals intense expression of the urotensin II gene in motoneurones of the spinal cord. Proc.Natl.Acad.Sci.U.S.A. 1998 PMID: 9861051

Urotensin II (human)

Tocris Bioscience, part of Bio-Techne | Catalog # 1642

Key Product Details

Biological Activity for Urotensin II (human)

Technical Data for Urotensin II (human)

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Urotensin II (human)

Product Documents for Urotensin II (human)

COA

Certificate of Analysis

SDS

CONTACT INFORMATION

保持关注