UPF 1069

Name: UPF 1069
Brand: Tocris Bioscience
SKU: 3736

Tocris Bioscience, part of Bio-Techne | Catalog # 3736

COA / SDS

PARP-2 inhibitor

Discontinued Product

3736 has been discontinued. View all Poly(ADP-ribose) Polymerase Inhibitors products.

Key Product Details

Description:	PARP-2 inhibitor
Chemical Name:	5-(2-Oxo-2-phenylethoxy)-3,4-dihydroisoquinolin-1(2H)-one
Purity:	≥99% (HPLC)
Molecular Weight:	279.29

View Full Technical Details for UPF 1069

Technical Data
Citations

Biological Activity for UPF 1069

Selective poly(ADP-ribose) polymerase (PARP) 2 inhibitor (IC₅₀ values are 0.3 and 8.0 μM for PARP-2 and PARP-1 respectively).

Technical Data for UPF 1069

M. Wt	279.29
Formula	C₁₇H₁₃NO₃
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	1048371-03-4
PubChem ID	25015515
InChi Key	JJWMRRNGWSITSQ-UHFFFAOYSA-N
Smiles	O=C2NC=CC1=C(OCC(C3=CC=CC=C3)=O)C=CC=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for UPF 1069

References are publications that support the biological activity of the product.

Pellicciari On the way to selective PARP-2 inhibitors. Design, synthesis and preliminary evaluation of a series of isoquinolinone derivatives. Chem.Med.Chem
Moroni Selective PARP-2 inhibitors increase apoptosis in hippocampal slices but protect cortical cells in models of post-ischaemic brain damage. Br.J.Pharmacol. 2009 PMID: 19422384

UPF 1069

Tocris Bioscience, part of Bio-Techne | Catalog # 3736

Key Product Details

Biological Activity for UPF 1069

Technical Data for UPF 1069

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for UPF 1069

Product Documents for UPF 1069

COA

Certificate of Analysis

SDS

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