UNC 1215, acid

Tocris Bioscience, part of Bio-Techne | Catalog # 7759

Functionalized L3MBTL3 ligand for PROTACs
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Key Product Details

Description

Functionalized L3MBTL3 ligand for PROTACs

View all Functionalized E3 Ligand Building Blocks »

Product Description

UNC 1215, acid is a functionalized L3MBTL3 ligand for PROTAC® research and development. L3MBTL3-recruiting PROTACs induce nuclear-specific protein degradation of target proteins, such as FKBP12(F36V) and BRD2. UNC 1215, acid contains a carboxylic acid handle ready for conjugation to a target protein ligand.

Part of a range of functionalized tool molecules for PROTAC&reg Degrader R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Product Specifications

Molecular Weight

801.78

Formula

C33H43N5O4.2CF3CO2H

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

4-[[2,5-Bis[[4-(1-pyrrolidinyl)-1-piperidinyl]carbonyl]phenyl]amino]benzoic acid ditrifluoroacetate

InChI Key

FONQYEMRSJVSSN-UHFFFAOYSA-N

SMILES

OC(C1=CC=C(NC2=C(C=CC(C(N3CCC(CC3)N4CCCC4)=O)=C2)C(N5CCC(CC5)N6CCCC6)=O)C=C1)=O.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for UNC 1215, acid

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for UNC 1215, acid

For research use only

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