UK 14,304
Tocris Bioscience, part of Bio-Techne | Catalog # 0425
α2 agonist
Product Description
UK 14,304 is a full α2 adrenergic agonist. Centrally active following systemic administration in vivo.Water-soluble Salt also available.
Product Specifications
Molecular Weight
292.14
Formula
C11H10BrN5
Storage
Store at RT
Chemical Name
5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline
CAS Number
59803-98-4
PubChem ID
2435
InChI Key
XYLJNLCSTIOKRM-UHFFFAOYSA-N
SMILES
BrC1=C(NC2=NCCN2)C=CC2=NC=CN=C12
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 100 |
Preparing Stock Solutions
for UK 14,304
The following data is based on the product molecular weight 292.14
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.42 mL | 17.12 mL | 34.23 mL |
| 5 mM | 0.68 mL | 3.42 mL | 6.85 mL |
| 10 mM | 0.34 mL | 1.71 mL | 3.42 mL |
| 50 mM | 0.07 mL | 0.34 mL | 0.68 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Chopin Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in rats with unilateral 6-hydroxyDA lesions of the nigrostriatal pathway. J.Pharmacol.Exp.Ther. 1999 PMID: 9918591
- Macdonald Gene targeting - homing in on α2-adrenoceptor-subtype function. TiPS 1997 PMID: 9227000
- Andorn Specific [3H]UK-14,304 binding in human cortex occurs at multiple high affinity states with α2-adrenergic selectivity and different affinities for GTP. Life Sci. 1988 PMID: 2904634
Product Specific Notices for UK 14,304
For research use only
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