UCLA GP130 2
Tocris Bioscience, part of Bio-Techne | Catalog # 6583
gp130 agonist; brain penetrant and neuroprotectant
Key Product Details
Description
gp130 agonist; brain penetrant and neuroprotectant
Product Description
UCLA GP130 2 is a gp130 agonist. Protects against NMDA-induced toxicity in primary hippocampal neurons in vitro. Increases STAT3 phosphorylation in SH-SY5Y cells. Brain penetrant.Product Specifications
Molecular Weight
270.32
Formula
C15H11FN2S
Storage
Store at +4°C
Purity
≥98% (HPLC)
Chemical Name
N-(4-Fluorophenyl)-4-phenyl-2-thiazolamine
CAS Number
339303-87-6
PubChem ID
1284592
InChI Key
HXVFUSRCVKYALB-UHFFFAOYSA-N
SMILES
FC1=CC=C(C=C1)NC2=NC(C3=CC=CC=C3)=CS2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 27.03 | 100 | |
| Ethanol | 27.03 | 100 |
Preparing Stock Solutions
for UCLA GP130 2
The following data is based on the product molecular weight 270.32
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.70 mL | 18.50 mL | 36.99 mL |
| 5 mM | 0.74 mL | 3.70 mL | 7.40 mL |
| 10 mM | 0.37 mL | 1.85 mL | 3.70 mL |
| 50 mM | 0.07 mL | 0.37 mL | 0.74 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Alam A small molecule mimetic of the humanin peptide as a candidate for modulating NMDA-induced neurotoxicity. ACS Chem.Neurosci. 2018 PMID: 29161500
Product Specific Notices for UCLA GP130 2
For research use only
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