U 73122

Tocris Bioscience, part of Bio-Techne | Catalog # 1268

Phospholipase C inhibitor
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Key Product Details

Description

Phospholipase C inhibitor

View all Phospholipase Inhibitors »

Product Description

U 73122 is a phospholipase C inhibitor. Inhibits agonist-induced platelet aggregation with IC50 values of 1-5 μM. Potently inhibits human polymorphonuclear neutrophil adhesion on biological surfaces (IC50 < 50 nM) and exhibits antinociceptive activity in vivo. Also activates TRPM4 and inhibits TRPM3 channels.

Negative Control also available.

Licensing Information

Sold with the permission of Pharmacia

Product Specifications

Molecular Weight

464.65

Formula

C29H40N2O3

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

1-[6-[[(17β)-3-Methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-1H-pyrrole-2,5-dione

CAS Number

112648-68-7

PubChem ID

104794

InChI Key

LUFAORPFSVMJIW-ZRJUGLEFSA-N

SMILES

[H][C@]23[C@@]([C@]([H])(CC[C@@H]4NCCCCCCN5C(C=CC5=O)=O)[C@]4(C)CC3)([H])CCC1=CC(OC)=CC=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Please refer to these solubility guidelines for U 73122 (Cat. No. 1268).

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Product Documents for U 73122

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for U 73122

For research use only

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