TUG 891
Tocris Bioscience, part of Bio-Techne | Catalog # 4601
Potent and selective FFA4 (GPR120) agonist
Key Product Details
Description
Potent and selective FFA4 (GPR120) agonist
Product Description
TUG 891 is a potent FFA4 (GPR120) agonist (pEC50 values are 7.36 and 7.77 for human and mouse GPR120 respectively). Selective for GPR120 over free fatty acid receptors (pEC50 = 4.19 for FFA1; displays no activity at FFA2 or FFA3). Cell permeable.Licensing Information
Sold under license from the University of Southern Denmark.Product Specifications
Molecular Weight
364.41
Formula
C23H21FO3
Storage
Store at RT
Purity
≥98% (HPLC)
Chemical Name
4-[(4-Fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]-benzenepropanoic acid
CAS Number
1374516-07-0
PubChem ID
57522038
InChI Key
LPGBXHWIQNZEJB-UHFFFAOYSA-N
SMILES
FC1=CC(COC2=CC=C(CCC(O)=O)C=C2)=C(C3=CC=C(C)C=C3)C=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 36.44 | 100 |
Preparing Stock Solutions
for TUG 891
The following data is based on the product molecular weight 364.41
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.74 mL | 13.72 mL | 27.44 mL |
| 5 mM | 0.55 mL | 2.74 mL | 5.49 mL |
| 10 mM | 0.27 mL | 1.37 mL | 2.74 mL |
| 50 mM | 0.05 mL | 0.27 mL | 0.55 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Shimpukade Discovery of a potent and selective GPR120 agonist. J.Med.Chem. 2012 PMID: 22519963
Product Specific Notices for TUG 891
For research use only
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