Treprostinil

Tocris Bioscience, part of Bio-Techne | Catalog # 5349

Potent prostacyclin (PGI2) analog
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Key Product Details

Description

Potent prostacyclin (PGI2) analog

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Product Description

Treprostinil is a potent prostacyclin (PGI2) analog (EC50 values are 0.6, 1.9 and 6.2 nM at DP1, IP and EP2 receptors respectively). Causes vasodilation of human pulmonary arteries and inhibits NFκB nuclear translocation in human alveolar macrophages in vitro.

Product Specifications

Molecular Weight

390.51

Formula

C23H34O5

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

2-[[(1R,2R,3aS,9aS)-2,3,3a,4,9,9a-Hexahydro-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl]oxy]acetic acid

CAS Number

81846-19-7

PubChem ID

6918140

InChI Key

PAJMKGZZBBTTOY-ZFORQUDYSA-N

SMILES

O[C@H](C3)[C@H](CC[C@@H](O)CCCCC)[C@@]([C@@]3([H])C2)([H])CC1=C2C(OCC(O)=O)=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 39.05 100
Ethanol 19.53 50

Preparing Stock Solutions for Treprostinil

The following data is based on the product molecular weight 390.51

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.56 mL 12.80 mL 25.61 mL
5 mM 0.51 mL 2.56 mL 5.12 mL
10 mM 0.26 mL 1.28 mL 2.56 mL
50 mM 0.05 mL 0.26 mL 0.51 mL

Calculators

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Product Documents for Treprostinil

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Treprostinil

For research use only

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