TR 14035

Tocris Bioscience, part of Bio-Techne | Catalog # 6908

Potent integrin α4β7 and α4β1 (VLA-4) antagonist; orally bioavailable
Catalog #
Availability
Size / Price
Qty
6908/10
6908/50
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Description

Potent integrin α4β7 and α4β1 (VLA-4) antagonist; orally bioavailable

View all Integrin Receptor Inhibitors »

Product Description

TR 14035 is a potent integrin α4β7 and α4β1 antagonist (IC50 values are 7 and 87 nM, respectively). Inhibits binding of HEK 293 cells to osteopontin forms. Orally bioavailable.

Product Specifications

Molecular Weight

474.33

Formula

C24H21Cl2NO5

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

(αS)-α-[(2,6-Dichlorobenzoyl)amino]-2',6'-dimethoxy[1,1'-biphenyl]-4-propanoic acid

CAS Number

232271-19-1

PubChem ID

9912743

InChI Key

DRSJLVGDSNWQBI-SFHVURJKSA-N

SMILES

COC1=CC=CC(OC)=C1C1=CC=C(C[C@H](NC(=O)C2=C(Cl)C=CC=C2Cl)C(O)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 47.43 100
Ethanol 9.49 20

Preparing Stock Solutions for TR 14035

The following data is based on the product molecular weight 474.33

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.11 mL 10.54 mL 21.08 mL
5 mM 0.42 mL 2.11 mL 4.22 mL
10 mM 0.21 mL 1.05 mL 2.11 mL
50 mM 0.04 mL 0.21 mL 0.42 mL

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

x
=
x

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background References

References are publications that support the biological activity of the product.

Product Documents for TR 14035

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for TR 14035

For research use only

Privacy Policy
Cookie Policy
Site Map
© Copyright 2026 Bio-Techne. All Rights Reserved. All trademarks and registered trademarks are the property of Bio-Techne and its brands unless otherwise specified.