Tocriscreen Kinase Inhibitor 3.0 New

Name: Tocriscreen Kinase Inhibitor 3.0
Brand: Tocris Bioscience
SKU: 7844

Tocris Bioscience a Bio-Techne Brand

Catalog # 7844

Citations (12)

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Key Product Details

Description:

A bioactive compound library of 210 kinase inhibitors (100 μL 10 mM DMSO solutions) for high-throughput screening, high-content screening and chemical biology applications

Key Format Details:

96-well racks with TrakMate tubes & SepraSeal caps
Pre-dissolved in DMSO
Compounds arranged 80 per rack with 3 racks per library

Many compounds are exclusive to Tocris
Full chemical and biological data available
Exceptional purity

Kinase subfamilies targeted by the Tocriscreen Kinase Inhibitor 3.0 library

Major IUPHAR kinase subfamilies covered by Tocriscreen Kinase Inhibitor 3.0 Library. TK (tyrosine kinase, 29%); CMGC (includes CDK, MAPK, GSK3 and CLK families, 19%); TKL (tyrosine kinase-like, 16%); AGC (includes PKA, PKG and PKC families, 11%); Atypical (7%); CAMK, (calcium/calmodulin-dependent protein kinases, 4%) and Other Kinases (includes CAMKK, CK1 and STE, 14%).

View Full Technical Details for Tocriscreen Kinase Inhibitor 3.0

Product Description for Tocriscreen Kinase Inhibitor 3.0

Tocriscreen Kinase Inhibitor 3.0 library is a collection of 210 kinase inhibitors supplied pre-dissolved in DMSO (100 μL 10 mM solution). The Tocriscreen Kinase Inhibitor Library contains compounds targeting >60 different kinases, including extensive coverage of well-established targets such as VEFGR and AKT, as well as novel targets such as Haspin and DYRK. The Tocriscreen Kinase Inhibitor 3.0 library is suitable for high-throughput screening (HTS), cell based high-content screening (HCS) and chemical biology applications.

If this library does not suit your needs, please submit your requirements through our Tocriscreen PRO custom compound library service.

Request Compound List

A list of the compounds available in the Tocriscreen Kinase Inhibitor 3.0 can be requested in Excel or SD format via our Tocriscreen & Custom Library Inquiries form.

Technical Data for Tocriscreen Kinase Inhibitor 3.0

Storage	Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Citations for Tocriscreen Kinase Inhibitor 3.0 (12)

Showing 1 - 10 of 12 citations Showing All

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Citations are publications that use Bio-Techne products. Selected citations for Tocriscreen Kinase Inhibitor 3.0 include:

Gull et al. (2022) Screening of chemical libraries using xenopus embryos and tadpoles for phenotypic drug discovery. Cold Spring Harb.Protoc.. 2022;
PMID: 36180216
Carlson et al. (2022) Discovery and characterization of multiple classes of human CatSper blockers. Chem Med Chem. 17:e202000499
PMID: 35644882
Lee et al. (2021) A screen of kinase inhibitors reveals a potential role of Chk1 in regulating Hydra head regeneration and maintenance. Int J Dev Biol. 65:523
PMID: 34549798
Hewage et al. (2020) Chemical manipulation of abscisic acid signaling: a new approach to abiotic and biotic stress management in agriculture. Adv.Sci.. 7:2001265
PMID: 32999840
Wang et al. (2019) EGFR-Aurka signaling rescues polarity and regeneration defects in dystrophin-deficient muscle stem cells by increasing asymmetric divisions. Cell Stem Cell. 24:419
PMID: 30713094
Moret et al. (2019) Cheminformatics tools for analyzing and designing optimized small-molecule collections and libraries. Cell Chem Biol. 26:765
PMID: 30956147
Chaudhari et al. (2019) Transient c-Src Suppression During Endodermal Commitment of Human Induced Pluripotent Stem Cells Results in Abnormal Profibrotic Cholangiocyte-Like Cells. Stem Cells. 37:306
PMID: 30471152
Yang et al. (2019) NTRK1 is a positive regulator of YAP oncogenic function. Oncogene. 38:2778
PMID: 30542115
Azad et al. (2018) A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis. Nat Commun. 9:1061
PMID: 29535383
Moeschler et al. (2018) 1-Benzyl-3-cetyl-2-methylimidazolium Iodide (NH125) Is a Broad-Spectrum Inhibitor of Virus Entry with Lysosomotropic Features. Viruses. 10:E306
PMID: 29874821
Tomilov et al. (2018) Idebenone is a cytoprotective insulin sensitizer whose mechanism is Shc inhibition. Pharmacol Res. 137:89
PMID: 30290222
Markussen et al. (2018) GSK3 is a negative regulator of the thermogenic program in brown adipocytes. Sci.Rep.. 8:3469
PMID: 29472592

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Showing 1 - 10 of 12 citations Showing All

Product Documents for Tocriscreen Kinase Inhibitor 3.0

COA

Certificate of Analysis is currently unavailable on-line. Please contact Customer Service.