TMN 355

Name: TMN 355
Brand: Tocris Bioscience
SKU: 4152
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 4152

(1)

Citations (3)

COA / SDS

Cyclophilin A inhibitor

Discontinued Product

4152 has been discontinued. View all Miscellaneous Compounds products.

Key Product Details

Description:	Cyclophilin A inhibitor
Chemical Name:	2-Chloro-N-[(9H-fluoren-9-ylamino)carbonyl]-6-fluorobenzamide
Purity:	≥98% (HPLC)
Molecular Weight:	380.8

View Full Technical Details for TMN 355

Technical Data
Citations / Reviews (1)

Biological Activity for TMN 355

TMN 355 is a potent cyclophilin A inhibitor (IC₅₀ = 1.52 nM). Approximately 27 times more potent than cyclosporin A (Cat. No. 1101).

Technical Data for TMN 355

M. Wt	380.8
Formula	C₂₁H₁₄ClFN₂O₂
Storage	Store at RT
Purity	≥98% (HPLC)
CAS Number	1186372-20-2
PubChem ID	44249042
InChi Key	SFNLLCUAISZNRV-UHFFFAOYSA-N
Smiles	ClC1=C(C(NC(NC2C(C=CC=C4)=C4C3=C2C=CC=C3)=O)=O)C(F)=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for TMN 355

References are publications that support the biological activity of the product.

Ni Discovering potent small molecule inhibitors of cyclophilin A using de novo drug design approach. J.Med.Chem. 2009 PMID: 19691347

TMN 355

Tocris Bioscience, part of Bio-Techne | Catalog # 4152

Key Product Details

Biological Activity for TMN 355

Technical Data for TMN 355

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for TMN 355

Product Documents for TMN 355

COA

Certificate of Analysis

SDS

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