Tianeptine sodium salt

Name: Tianeptine sodium salt
Brand: Tocris Bioscience
SKU: 1972

Tocris Bioscience, part of Bio-Techne | Catalog # 1972

Citations (82)

COA / SDS

Selective facilitator of 5-HT uptake; antidepressant

Discontinued Product

1972 has been discontinued. View all 5-HT Transporter Compounds products.

Key Product Details

Description:	Selective facilitator of 5-HT uptake; antidepressant
Chemical Name:	7-[(3-Chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid sodium salt
Purity:	≥99% (HPLC)
Molecular Weight:	458.93

View Full Technical Details for Tianeptine sodium salt

Technical Data
Citations

Biological Activity for Tianeptine sodium salt

Tianeptine sodium salt is a selective facilitator of 5-HT uptake in vitro and in vivo. Has no affinity for a wide range of receptors, including 5-HT and dopamine (IC₅₀ > 10 μM) and has no effect on noradrenalin or dopamine uptake. Antidepressant, analgesic and neuroprotective following systemic administration in vivo.

Technical Data for Tianeptine sodium salt

M. Wt	458.93
Formula	C₂₁H₂₄ClN₂NaO₄S
Storage	Desiccate at RT
Purity	≥99% (HPLC)
CAS Number	30123-17-2
PubChem ID	23663953
InChi Key	ZLBSUOGMZDXYKE-UHFFFAOYSA-M
Smiles	[Na+].CN1C2=CC=CC=C2C(NCCCCCCC([O-])=O)C2=CC=C(Cl)C=C2S1(=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for Tianeptine sodium salt

References are publications that support the biological activity of the product.

Mennini Tianeptine, a selective enhancer of serotonin uptake in rat brain. Naunyn-Schmied.Arch.Pharmacol.
Uzbay Analgesic effect of tianeptine in mice. Life Sci. 1999 PMID: 10227587
Plaisant Neuroprotective properties of tianeptine: interactions with cytokines. Neuropharmacology 2003 PMID: 12681378
Kato and Weitsch Neurochemical profile of tianeptine, a new antidepressant drug. Clin.Neuropharmacol. 1988 PMID: 3052825

Tianeptine sodium salt

Tocris Bioscience, part of Bio-Techne | Catalog # 1972

Key Product Details

Biological Activity for Tianeptine sodium salt

Technical Data for Tianeptine sodium salt

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Tianeptine sodium salt

Product Documents for Tianeptine sodium salt

COA

Certificate of Analysis

SDS

CONTACT INFORMATION

保持关注