Thrombin Receptor Agonist Peptide

Name: Thrombin Receptor Agonist Peptide
Brand: Tocris Bioscience
SKU: 1185

Tocris Bioscience, part of Bio-Techne | Catalog # 1185

Citations (4)

COA / SDS

Causes platelet aggregation and secretion

Key Product Details

Description:	Causes platelet aggregation and secretion
Alternative Names:	TRAP
Purity:	≥95% (HPLC)
Molecular Weight:	1739.95

View Full Technical Details for Thrombin Receptor Agonist Peptide

Technical Data
Citations

Biological Activity for Thrombin Receptor Agonist Peptide

Thrombin Receptor Agonist Peptide is an agonist at the thrombin receptor; causes platelet aggregation (EC₅₀ = 4 μM) and secretion.

Technical Data for Thrombin Receptor Agonist Peptide

M. Wt	1739.95
Formula	C₈₁H₁₁₈N₂₀O₂₃
Single Letter Sequence	SFLLRNPNDKYEPF
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	137339-65-2
PubChem ID	16131180
InChi Key	OXHYRVSBKWIFES-WWSDOYNLSA-N
Smiles	[H]N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Thrombin Receptor Agonist Peptide

Solubility

Soluble to 0.9mg/ml in water

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References for Thrombin Receptor Agonist Peptide

References are publications that support the biological activity of the product.

Vassallo Structure-function relationships in the activation of platelet thrombin receptors by receptor-derived peptides. J.Biol.Chem. 1992 PMID: 1313429
Vu Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 1991 PMID: 1672265
Huang 'Thrombin' receptor-directed ligand accounts for activation by thrombin of platelet phospholipase C and accumulation of 3-phosphorylated phosphoinositides. J.Biol.Chem. 1991 PMID: 1655750